US 6048730

This patent was applied by and granted to Novartis

US 6048730

Claim 1A chimeric gene functional in a plant cell, which chimeric gene comprises:

a) at a position 5′ to coding region (c), a plant-expressible promoter sequence;
b) at a position 3′ to coding region (c), a terminator signal sequence; and
c) a coding region of an aphIV gene, which coding region:

  1. encodes a functional hygromycin phosphotransferase enzyme or functional portion thereof; and
  2. is positioned between such plant-expressible promoter sequence (a) and such terminator signal sequence (b) so as to be expressible,
    wherein expression of such coding region in a plant cell confers resistance to hygromycin B on such plant cell and
    wherein such resistance to hygromycin B is capable of providing a basis for selection of such plant cell.