Applications by Paradigm Genetics Inc.

Paradigm Genetics Inc. (Research Triangle Park, N.C., US) was founded in 1997 and went public in 2000. In its early years Paradigm’s business statements emphasised making use of genomics information obtained from Arabidopsis, for extensions into crop plants via agricultural biotechnology.  During this time it sequenced a large number of Arabidopsis ESTs.

In 2004 Paradigm changed its name to Icoria Inc.  Icoria moved into medical biotechnology and sold assets relating to its agricultural genomics business to Monsanto Co.  In the period 1997-2004 Monsanto had extensive ties to the Arabidopsis genome sequencing project, and extensive bulk sequence patent filings in crop plants (e.g. rice, maize and cotton), although because of non-publication requests by Monsanto and other procedural matters, many of these were not known to the public until 2004 or later (see for exampleUS 2004/31072, which claims 285,684 sequences mostly from soybean, with applications in many other related crop plants).

We have been able to find 9 patent applications with Paradigm Genetics Inc. as the applicant or correspondent.  Since the 2004 acquisition these may now be assigned to Monsanto, although USPTO assignment information provided by the applicants is not always kept up to date.

Since all 9 patents are very similar, and each claim ~1000 ESTs from Arabidopsis, we have chosen one, US2001/44940 A1 (the ‘940 application) to discuss below.

See bar graphs showing the portions of the Arabidopsis genome that are covered by patent applications and granted patents that are assigned to Paradigm Genetics Inc.

Search Strategy

Since the major players in patenting of Arabidopsis sequences are known (from press releases and biotechnology publications), company names can be used in searches.  In this case Paradigm Genetics was used as part of a search strategy.

The Paradigm Genetics Inc. patents discussed  in this section were identified using the following search strategy.

Search details
Date of search 18 05 2006
Database searched Patent Lens, accessible at www.patentlens.net
Type of search Structured Search
Collections searched US-A, WO-A, US-B, EP-B, AU-B (add link to “Documents in  Collection” which will take you to a web page that describes the extent of the collection.)
Search terms (arabidopsis AND thaliana) AND (paradigm AND genetics)
Results 361
Comments Of the 361 results identified using these search terms, 9 results were identified as having bulk sequence claims based on the content of their titles, abstracts, and claims.  The correspondent named on these applications is PARADIGM GENETICS, INC., 104 ALEXANDER DRIVE, BUILDING 2, P O BOX 14528, RTP, NC, 277094528.

You may find other patents or applications of interest based on your particular circumstances.  We encourage you to go to the Patent Lens to adapt this search to your needs or to update this search.  We invite you to provide comments on patents or applications that you see below or that you identify in your own searches which may be of interest to those reading this landscape, by going to the Add Comment link.

As a precaution, a further search was performed:  this time no assignee/applicant/correspondent names were used.  Instead the strategy conducted was:

Search details
Date of search 14 06 2006
Database searched Patent Lens, accessible at www.patentlens.net
Type of search Structured Search
Collections searched US-A, WO-A, US-B, EP-B, AU-B (add link to “Documents in  Collection” which will take you to a web page that describes the extent of the collection.)
Search terms (Arabidopsis AND thaliana) AND ((SEQ AND ID) in claims)
Results 3,824
Comments The results were sorted by relevance score, and the top 300 patent documents were investigated.  Whilst new and interesting Arabidopsis patents appeared, no-other Paradigm applications or patents covering bulk sequence applications could be identified (although some may have been missed by this search).

You may find other patents or applications of interest based on your particular circumstances.  We encourage you to go to the Patent Lens to adapt this search to your needs or to update this search.  We invite you to provide comments on patents or applications that you see below or that you identify in your own searches which may be of interest to those reading this landscape, by going to the Add Comment link.