Arabidopsis Genome Maps

Sequences from US Patents Mapped onto the Chromosomes of Arabidopsis

By performing a modification of the analysis of Jensen and Murray (Science. 2005 Oct 14;310(5746):239-40.), a member of our group was able to map patented sequences  from US granted patents onto the Arabidopsis chromosomes.  The following 5 maps demonstrate the distribution of patents across Arabidopsischromosomes.

Note carefully the limitations of this analysis:

  • Only granted US patents were analysed
  • Only patent sequence details for DNA sequences were analysed not claims on protein sequences
  • Only sequences recorded in NCBI’s Patent database were included (June  2006 version)
  • Only sequences appearing in the claims section were analysed
  • No regard was made of the claim language, or of claim scope (no attempt was made to identify claims to other homologous or related sequences)
  • No regard was given to claims originating from overlap of claims from other species (i.e. we identified only “identical” Arabidopsis sequences from patents).

(see below for more details of these analyses)

(Chromosome 1 = 30Mb)

In all chromsome maps the Y-axis is the number of patents found within 300Kb sections of the chromosome map.

Chromosome 2

Chromosome 3:

Note:

  • The Y-axis range is 0 to 10 patents
  • The locus map location 13,500,000 is a patent “hot spot” and contains 47 patents (with references to 78 individual GenBank sequences) For more details of this “hot spot” see the text below.
Chromosome 4

Note:

Sequences contained in US applications were not included in any of these chromosome maps.

All of the bulk sequence applications discussed in the text below are not included in this map.

Chromosome 5

The same Y-axis scale has been used throughout, to allow the user to compare the relative “intensities” of patenting activity on each of the chromosomes.

Different X-axis scales have been used, to allow optimal resolution of patent activity.  The relative sizes of the different chromosomes are represented in the chromosome graphic below the X-axis.

Note:  Because of the nature of the analysis above (see the notes on the right of the maps above), the mapped sequences are likely to greatly under-represent the true degree of patent activity on theArabidopsis genome!

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