Arabidopsis Genome Maps

Arabidopsis Genome Maps of Sequences appearing in US-patent applications

By performing a modification of the analysis of Jensen and Murray (Science. 2005 Oct 14;310(5746):239-40.), a member of our group was able to map sequences appearing in the claims section of US patent applications onto the Arabidopsischromosomes.  The following 5 maps demonstrate the distribution of sequences across Arabidopsis chromosomes.

Note carefully the limitations of this analysis:

  • Only sequences from US applications were analysed
  • Only patent sequence details for DNA sequences were analysed not claims on protein sequences
  • By our estimates >90% of relevant US-A patent documents have been included in this analysis
  • Only sequences appearing in the claims section were analysed
  • No regard was made of the claim language, or of claim scope (no attempt was made to identify claims to other homologous or related sequences)
  • No regard was given to claims originating from overlap of claims from other species (i.e. we identified only “identical” Arabidopsis sequences from patents).

(see below for more details of these analyses)

(Chromosome 1 = 30Mb)

In all chromosome maps the Y-axis is the number of patent applications found within 300Kb sections of the chromosome map.

Chromosome 2
The hot-spot at 3.6MB has 1077 sequences from patent applications mapped to it (Y scale = 200 patents)

Chromosome 3:

Note:

  • The Y-axis range is 0 to 200 patents
  • The locus map location 13,500,000 is a patenting “hot spot” and 1336 sequences from applications are mapped here.
  •  For more details of this “hot spot” see the comments in the previous section.
Chromosome 4

Note:

Sequences contained in US granted patents were not included in these chromosome maps. Although it is unlikely that the inclusion of such data would change the map significantly.

As far as possible, bulk sequence applications have been included in this analysis.

Chromosome 5

Different X-, and Y-axis scales has been used throughout, to allow the best possible view of all data.

Note:  Because of the nature of the analysis above (see the notes on the left of the maps above), the mapped sequences are likely to greatly under-represent the true degree of patent activity on the Arabidopsis genome!