Inducible promoters

Summary

As their name says, the activity of these promoters is induced by the presence or absence of biotic or abiotic factors. Inducible promoters are a very powerful tool in genetic engineering because the expression of genes operably linked to them can be turned on or off at certain stages of development of an organism or in a particular tissue.

This section presents a general view of patents directed to promoters whose activity is triggered by either chemical or physical factors. The patents discussed in this section are about general promoter systems and their uses and do not encompass particular promoters. There are virtually hundreds of inducible promoters that vary according to the organism source and cells or tissues where they regulate gene transcription. Thus, this section only discusses patents drawn to inducible promoter systems that are regulated by particular chemical or physical factors.

The analyzed patents on inducible promoters are grouped as:

  • Chemically-regulated promoters, including promoters whose transcriptional activity is regulated by the presence or absence of alcohol, tetracycline, steroids, metal and other compounds.
  • Physically-regulated promoters, including promoters whose transcriptional activity is regulated by the presence or absence of light and low or high temperatures.